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Why does it feel effortful to be precise?

April 2, 2019 admin Leave a comment

Our eye movements are controlled by a relatively simple circuit in the brainstem. Remarkably, it seems to operate with less…

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Recent Posts

  • Neurons that rapidly change their selectivity February 28, 2023
  • What does the claustrum do? February 9, 2022
  • Hunger increases reinforcement learning rate May 26, 2021
  • Frontal brain damage makes decisions less biased February 13, 2021
  • Drugs affect subtypes of Parkinson’s disease differently December 26, 2020
  • Parkinson’s medication has opposite effects on two kinds of motivation November 29, 2020
  • Are working memory and visual search windows into the same neural process? October 1, 2020
  • Pupil size betrays contents of working memory October 25, 2019
  • Dopamine can make our working memory more or less flexible September 19, 2019
  • Neural model of working memory July 29, 2019

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    Sanjay ManoharFollow

    Cognition is a tool we use for understanding the brain around us.

    Sanjay Manohar
    chrost_hugoHugo Chrost@chrost_hugo·

    I am very happy that you liked it Nick! It a very beginning!

    #MedTwitter #neuroscience https://twitter.com/nickmmark/status/1631416090919317504

    Reply on Twitter 1631438899548672000Retweet on Twitter 16314388995486720005Like on Twitter 163143889954867200013
    BrainInTheMindSanjay Manohar@BrainInTheMind·

    Are you excited about neural mechanisms of working memory, and could fill a short postdoc vacancy in Oxford?
    https://www.jobs.ac.uk/job/CXK511/postdoctoral-research-associate

    Reply on Twitter 1626037895113981952Retweet on Twitter 162603789511398195218Like on Twitter 16260378951139819527
    OxNeuroOxford Neuroscience@OxNeuro·

    Congratulations Eda Mizrak! @damnmemory @BrainInTheMind @NDCNOxford https://twitter.com/PsychScience/status/1621192294069043201

    Reply on Twitter 1621513304421302273Retweet on Twitter 16215133044213022732Like on Twitter 16215133044213022734
    PetitetPierrePierre Petitet@PetitetPierre·

    Our latest on the relationship between apathy and impulsivity, within a behavioural task this time! With @MasudHusain @BrainInTheMind @sijiazhao92 and Dan Drew
    https://www.nature.com/articles/s41598-022-25882-z#citeas

    Reply on Twitter 1618885585057509376Retweet on Twitter 161888558505750937611Like on Twitter 161888558505750937625
    brognitionBrain and Cognition Lab@brognition·

    Viva celebration time for @srchekroud! Congratulations and thank you for all your MANY years in the lab from undergrad to RA to DPhil 🚀🔥🎓Thanks to examiners @BrainInTheMind and Daryl Fougnie!

    Reply on Twitter 1618287757927002112Retweet on Twitter 16182877579270021121Like on Twitter 161828775792700211250
    oliverharmsonOliver Härmson@oliverharmson·

    Chuffed to have successfully defended my doctoral dissertation with @LHuntNeuro and Sebastien Bouret on the neural substrates of cost-benefit decision-making! Thank you both for a really interesting exchange of ideas!

    2
    Reply on Twitter 1613121492878753797Retweet on Twitter 16131214928787537973Like on Twitter 161312149287875379735
    ExpBrainResExperimental Brain Research@ExpBrainRes·

    Risk-taking, dopamine, & the role of baseline endogenous dopamine levels in the emergence of impulse control disorders in #Parkinsons disease. A pharmacological manipulation in healthy volunteers.
    https://rdcu.be/c0hI9
    @BrainInTheMind @oxneuro @OxExpPsy @NDCNOxford @KLKrems

    Reply on Twitter 1595545715551637504Retweet on Twitter 15955457155516375049Like on Twitter 15955457155516375048
    dieNeurologinStephanie Hirschbichler@dieNeurologin·

    Dopamine increases risky choice while D2 blockade shortens decision time.

    My new paper about risky decision-making and dopamine is out.
    https://doi.org/10.1007/s00221-022-06501-9

    @BrainInTheMind thanks a million!
    @OxNeuro @OxExpPsy @NDCNOxford @KLKrems

    Reply on Twitter 1594719122633416713Retweet on Twitter 15947191226334167134Like on Twitter 15947191226334167134
    FieteGroupFieteGroup@FieteGroup·

    Thanks to the Swartz foundation @SwartzCompNeuro , the SfN Swartz prize committee and the SfN @SfNtweets !

    Touched to hear from so many brilliant female computational neuroscientists. For the young women and men in computational neuroscience — this is you next.

    (1/5)

    Reply on Twitter 1591894876341272582Retweet on Twitter 159189487634127258216Like on Twitter 1591894876341272582103
    postlelabpostlelab@postlelab·

    @kcs_adam 1/2 Lots of really good Perspectives in the @StokesNeuro Special Focus in JoCN, in addition to yours: Duncan, @nick_e_myers, @evaferedoes, @BrainInTheMind, @timbuschman and @MillerLabMIT , Buckley, @Alexandra_Pike +cast of 1000s, and @KiaNobre

    Reply on Twitter 1582823163175763968Retweet on Twitter 15828231631757639689Like on Twitter 158282316317576396823
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    Recent work

    • Neurons that rapidly change their selectivity
      The activity of neurons carries information because they become active only in particular situations. This is called ‘selectivity’, and it allows a group of neurons to signal the state of the world. We may remember things either by keeping neurons active, or by changing their selectivities. However, we haven’t really worked out how changing a neuron’s selectivity works, to help us perform tasks. Here in Bocincova et al. PNAS (2022) (free) we find that neurons in […]
    • What does the claustrum do?
      Here with colleagues from physiology, we review the clinical effects of damage to the claustrum in Atilgan et al. Brain (2022). The claustrum is a thin sheet of neurons in the frontal lobe. Very few reported cases have isolated claustrum damage. In those who did, the findings don’t clearly reflect what you might expect, given the known fMRI activations and connections of the claustrum. […]
    • Hunger increases reinforcement learning rate
      Sometimes we plan ahead, thinking about future consequences of our actions. Other times, we select actions based only on their immediate reward associations. Planning ahead is crucial to staying healthy, but might be affected by motivation. We asked whether hunger affects planned vs directly reinforced action (van Swieten, Bogacz & Manohar Cogn. Aff. Beh. Neurosci. 2021). We found that people learned quicker about action values when they were hungry. Hunger didn’t affect planning. […]
    • Frontal brain damage makes decisions less biased
      Learning from reinforcement is a classic way to study how brain areas contribute to adaptive behaviour. The most frontal parts of the brain probably contribute at a very high, abstract level. In this study (Manohar et al. Cortex 2021), we asked how confident people are in what they have learned. Underside of a human brain showing a part of the ventromedial prefrontal cortex. Healthy people are biased by previous choices, and by competing information, when making these […]
    • Drugs affect subtypes of Parkinson’s disease differently
      In this commentary, I discuss the implications of new work from Hanneke Den Ouden’s lab. The authors subdivided Parkinson’s disease patients into those with and without tremor, and found that learning was affected by dopamine in opposite directions in the two groups! […]
    • Parkinson’s medication has opposite effects on two kinds of motivation
      Patients with Parkinson’s disease lack the brain chemical dopamine. Dopamine is thought to signal upcoming rewards, and this might explain why patients on treatment can develop impulse control disorders. My lab is studying two different ways to motivate people. One way is to reward or punish them based on how well they do — like performance-related pay. The other way is to promise a guaranteed reward, which also tends to keep people motivated (even though they don’t have to). […]
    • Are working memory and visual search windows into the same neural process?
      When you recall an item from memory, a prompt usually brings associated parts of that item into mind. Could this process be the same thing that occurs when you search for a visual target? We tested a neural model designed to perform working memory tasks, to see if it could also perform visual search. The model retrieves information when a partial cue re-activates a pattern of neurons by associative pattern completion. This same process could occur when we look for an item that we have in mind: […]